Anti-PTPRE Antibody Picoband®

About this product

Boster Bio Anti-PTPRE Antibody Picoband® catalog # A05574-1. Tested in WB, IHC, ICC/IF, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

A05574-1-carrier-free

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Several alternatively spliced transcript variants of this gene have been reported, at least two of which encode a receptor-type PTP that possesses a short extracellular domain, a single transmembrane region, and two tandem intracytoplasmic catalytic domains; another one encodes a PTP that contains a distinct hydrophilic N-terminus, and thus represents a nonreceptor-type isoform of this PTP. Studies of the similar gene in mice suggested the regulatory roles of this PTP in RAS related signal transduction pathways, cytokine-induced SATA signaling, as well as the activation of voltage-gated K+ channels.

Synonyms

PTPRE; Receptor-type tyrosine-protein phosphatase epsilon; Protein-tyrosine phosphatase epsilon; R-PTP-epsilon; EC 3.1.3.48

Gene Name

PTPRE

Gene ID

5791

UniProt

P23469

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E.coli-derived human PTPRE recombinant protein (Position: Q74-H591) . Human PTPRE shares 94.2% and 94.8% amino acid (aa) sequence identity with mouse and rat PTPRE, respectively.

Clonality

Polyclonal

Applications

WB, IHC, ICC/IF, Flow Cytometry, ELISA

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

References & Citations

1. Elson, A., Kozak, C. A., Morton, C. C., Weremowicz, S., Leder, P. The protein tyrosine phosphatase epsilon gene maps to mouse chromosome 7 and human chromosome 10q26. Genomics 31: 373-375, 1996. 2. Krueger, N. X., Streuli, M., Saito, H. Structural diversity and evolution of human receptor-like protein tyrosine phosphatases. EMBO J. 9: 3241-3252, 1990. 3. Melhado, I. G., Anderson, L. L., Duncan, A. M. V., Jirik, F. R. The gene encoding protein-tyrosine phosphatase RPTP-epsilon (PTPRE) is assigned to human chromosome 10q26. Cytogenet. Cell Genet. 73: 168-170, 1996.

Storage Conditions

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Calculated Molecular Weight

81 kDa

Observed Molecular Weight

81 kDa

Applications Notes

6

Gene Name Synonym

Protein tyrosine phosphatase receptor type E

Protein Name

Receptor-type tyrosine-protein phosphatase epsilon

Isotype

Rabbit IgG

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.