Anti-MPLKIP Antibody Picoband®

About this product

Boster Bio Anti-MPLKIP Antibody Picoband® catalog # A10184-1. Tested in WB, ICC/IF, ELISA applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

A10184-1-carrier-free

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

The protein encoded by this gene localizes to the centrosome during mitosis and to the midbody during cytokinesis. The protein is phosphorylated by cyclin-dependent kinase 1 during mitosis and subsequently interacts with polo-like kinase 1. The protein is thought to function in regulating mitosis and cytokinesis. Mutations in this gene result in nonphotosensitive trichothiodystrophy.

Synonyms

MPLKIP; C7orf11; TTDN1; M-phase-specific PLK1-interacting protein; TTD non-photosensitive 1 protein

Gene Name

MPLKIP

Gene ID

136647

UniProt

Q8TAP9

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E.coli-derived human MPLKIP recombinant protein (Position: E135-C179) . Human MPLKIP shares 97.7% amino acid (aa) sequence identity with mouse MPLKIP.

Clonality

Polyclonal

Applications

WB, ICC/IF, ELISA

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

References & Citations

1. Botta, E., Offman, J., Nardo, T., Ricotti, R., Zambruno, G., Sansone, D., Balestri, P., Raams, A., Kleijer, W. J., Jaspers, N. G. J., Sarasin, A., Lehmann, A. R., Stefanini, M. Mutations in the C7orf11 (TTDN1) gene in six nonphotosensitive trichothiodystrophy patients: no obvious genotype-phenotype relationships. Hum. Mutat. 28: 92-96, 2007. 2. Jackson, C. E., Weiss, L., Watson, J. H. L. 'Brittle' hair with short stature, intellectual impairment and decreased fertility: an autosomal recessive syndrome in an Amish kindred. Pediatrics 54: 201-212, 1974. 3. Nakabayashi, K., Amann, D., Ren, Y., Saarialho-Kere, U., Avidan, N., Gentles, S., MacDonald, J. R., Puffenberger, E. G., Christiano, A. M., Martinez-Mir, A., Salas-Alanis, J. C., Rizzo, R., Vamos, E., Raams, A., Les, C., Seboun, E., Jaspers, N. G. J., Beckmann, J. S., Jackson, C. E., Scherer, S. W. Identification of C7orf11 (TTDN1) gene mutations and genetic heterogeneity in nonphotosensitive trichothiodystrophy. Am. J. Hum. Genet. 76: 510-516, 2005.

Storage Conditions

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Calculated Molecular Weight

19 kDa

Observed Molecular Weight

19 kDa

Gene Name Synonym

M-phase specific PLK1 interacting protein

Protein Name

M-phase-specific PLK1-interacting protein

Isotype

Rabbit IgG

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.