Anti-GP6 Antibody Picoband®

About this product

Boster Bio Anti-GP6 Antibody Picoband® catalog # A02208-1. Tested in WB, Flow Cytometry applications. This antibody reacts with Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

A02208-1

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

Enables collagen binding activity and collagen receptor activity. Acts upstream of or within collagen-activated tyrosine kinase receptor signaling pathway; peptidyl-tyrosine phosphorylation; and platelet aggregation. Located in cell surface and plasma membrane. Is expressed in bone marrow; femur; liver; and spleen. Human ortholog (s) of this gene implicated in blood platelet disease (multiple) ; coronary artery disease (multiple) ; and type 2 diabetes mellitus. Orthologous to human GP6 (glycoprotein VI platelet) .

Synonyms

GP6; Platelet glycoprotein VI; GPVI; Glycoprotein 6

Gene Name

GP6

Gene ID

243816

UniProt

P0C191

Host

Rabbit

Reactivity

Mouse

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of mouse GP6. Mouse GP6 shares 75% amino acid (aa) sequence identity with human GP6.

Clonality

Polyclonal

Applications

WB, Flow Cytometry

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

References & Citations

1. Boilard, E., Nigrovic, P. A., Larabee, K., Watts, G. F. M., Coblyn, J. S., Weinblatt, M. E., Massarotti, E. M., Remold-O'Donnell, E., Farndale, R. W., Ware, J., Lee, D. M. Platelets amplify inflammation in arthritis via collagen-dependent microparticle production. Science 327: 580-583, 2010. 2. Dumont, B., Lasne, D., Rothschild, C., Bouabdelli, M., Ollivier, V., Oudin, C., Ajzenberg, N., Grandchamp, B., Jandrot-Perrus, M. Absence of collagen-induced platelet activation caused by compound heterozygous GPVI mutations. Blood 114: 1900-1903, 2009. 3. zumi, Y., Uchiyama, T., Takayama, H. Molecular cloning, genomic structure, chromosomal localization, and alternative splice forms of the platelet collagen receptor glycoprotein VI. Biochem. Biophys. Res. Commun. 277: 27-36, 2000.

Storage Conditions

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Calculated Molecular Weight

35 kDa

Observed Molecular Weight

35 kDa

Applications Notes

6

Gene Name Synonym

Glycoprotein 6 platelet

Protein Name

Platelet glycoprotein VI

Isotype

Rabbit IgG

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.