Anti-GSTM2 Antibody Picoband®

About this product

Boster Bio Anti-GSTM2 Antibody Picoband® catalog # A04423-3. Tested in WB, IHC applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

A04423-3-carrier-free

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs.

Synonyms

GSTM2; GST4; Glutathione S-transferase Mu 2; EC 2.5.1.18; GST class-mu 2; GSTM2-2

Gene Name

GSTM2

Gene ID

14863

UniProt

P15626

Host

Rabbit

Reactivity

Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

A synthetic peptide corresponding to a sequence in the middle region of mouse GSTM2. Human GSTM2 shares 95.5% amino acid (aa) sequence identity with rat GSTM2.

Clonality

Polyclonal

Applications

WB, IHC

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

References & Citations

1. Mannervik, B. The isozymes of glutathione transferase. Adv. Enzymol. Relat. Areas Molec. Biol. 57: 357-417, 1985. 2. Pearson, W. R., Vorachek, W. R., Xu, S., Berger, R., Hart, I., Vannais, D., Patterson, D. Identification of class-mu glutathione transferase genes GSTM1-GSTM5 on human chromosome 1p13. Am. J. Hum. Genet. 53: 220-233, 1993. 3. Taylor, J. B., Oliver, J., Sherrington, R., Pemble, S. E. Structure of human glutathione S-transferase class mu genes. Biochem. J. 274: 587-593, 1991.

Storage Conditions

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Calculated Molecular Weight

26 kDa

Observed Molecular Weight

26 kDa

Gene Name Synonym

Glutathione S-transferase mu 2

Protein Name

Glutathione S-transferase Mu 2

Isotype

Rabbit IgG

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.