Anti-OMA1 Antibody Picoband®

About this product

Boster Bio Anti-OMA1 Antibody Picoband® catalog # A06260. Tested in WB, IHC, ICC/IF, Flow Cytometry, ELISA applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

A06260

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

Enables metalloendopeptidase activity. Involved in several processes, including HRI-mediated signaling; proteolysis; and regulation of mitochondrion organization. Located in mitochondrial inner membrane. Is active in mitochondrial intermembrane space.

Synonyms

OMA1; MPRP1; Metalloendopeptidase OMA1, mitochondrial; EC 3.4.24.-; Metalloprotease-related protein 1; MPRP-1; Overlapping with the m-AAA protease 1 homolog

Gene Name

OMA1

Gene ID

115209

UniProt

Q96E52

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E.coli-derived human OMA1 recombinant protein (Position: K256-H483) . Human OMA1 shares 83.3% amino acid (aa) sequence identity with both mouse and rat OMA1.

Clonality

Polyclonal

Applications

WB, IHC, ICC/IF, Flow Cytometry, ELISA

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

References & Citations

1. Bao, Y.-C., Tsuruga, H., Hirai, M., Yasuda, K., Yokoi, N., Kitamura, T., Kumagai, H. Identification of a human cDNA sequence which encodes a novel membrane-associated protein containing a zinc metalloprotease motif. DNA Res. 10: 123-128, 2003. 2. Fessler, E., Eckl, E.-M., Schmitt, S., Mancilla, I. A., Meyer-Bender, M. F., Hanf, M., Philippou-Massier, J., Krebs, S., Zischka, H., Jae, L. T. A pathway coordinated by DELE1 relays mitochondrial stress to the cytosol. Nature 579: 433-437, 2020. 3. Guo, X., Aviles, G., Liu, Y., Tian, R., Unger, B. A., Lin, Y.-H. T., Wiita, A. P., Xu, K., Correia, M. A., Kampmann, M. Mitochondrial stress is relayed to the cytosol by an OMA1-DELE1-HRI pathway. Nature 579: 427-432, 2020.

Storage Conditions

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Calculated Molecular Weight

60 kDa

Observed Molecular Weight

60 kDa

Applications Notes

6

Gene Name Synonym

OMA1 zinc metallopeptidase

Protein Name

Metalloendopeptidase OMA1, mitochondrial

Isotype

Rabbit IgG

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.