Anti-RIM1/RIMS1 Antibody Picoband®

About this product

Boster Bio Anti-RIM1/RIMS1 Antibody Picoband® catalog # A05490. Tested in WB, IHC, ELISA applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

A05490-carrier-free

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

The protein encoded by this gene is a RAS gene superfamily member that regulates synaptic vesicle exocytosis. This gene also plays a role in the regulation of voltage-gated calcium channels during neurotransmitter and insulin release. Mutations have suggested a role cognition and have been identified as the cause of cone-rod dystrophy type 7. Multiple transcript variants encoding different isoforms have been described for this gene.

Synonyms

RIMS1; KIAA0340; RAB3IP2; RIM1; Nbla00761; Regulating synaptic membrane exocytosis protein 1; Rab-3-interacting molecule 1; RIM 1; Rab-3-interacting protein 2

Gene Name

RIMS1

Gene ID

22999116837

UniProt

Q86UR5, Q99NE5

Host

Rabbit

Reactivity

Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E.coli-derived human RIM1/RIMS1 recombinant protein (Position: K49-E1456) .

Clonality

Polyclonal

Applications

WB, IHC, ELISA

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

References & Citations

1. Barragan, I., Marcos, I., Borrego, S., Antinolo, G. Molecular analysis of RIM1 in autosomal recessive retinitis pigmentosa. Ophthalmic Res. 37: 89-93, 2005. 2. Betz, A., Thakur, P., Junge, H. J., Ashery, U., Rhee, J.-S., Scheuss, V., Rosenmund, C., Rettig, J., Brose, N. Functional interaction of the active zone proteins Munc13-1 and RIM1 in synaptic vesicle priming. Neuron 30: 183-196, 2001. 3. Castillo, P. E., Schoch, S., Schmitz, F., Sudhof, T. C., Malenka, R. C. RIM1-alpha is required for presynaptic long-term potentiation. Nature 415: 327-330, 2002.

Storage Conditions

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Calculated Molecular Weight

189 kDa

Observed Molecular Weight

189 kDa

Gene Name Synonym

Regulating synaptic membrane exocytosis 1

Protein Name

Regulating synaptic membrane exocytosis protein 1

Isotype

Rabbit IgG

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.