Anti-MAP1 Antibody (Monoclonal, HM-1)

About this product

Boster Bio Anti-MAP1 Antibody (Monoclonal, HM-1) catalog # MA1056. Tested in IHC, WB applications. This antibody reacts with Mouse, Rat.

Specifications

Catalog number

MA1056

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

Microtubules are the ubiquitous cytoskeletal structural components that are involved in intracellular transport. They are composed of tubulin and microtubule-associated proteins (MAPs) . MAP1 is one of the major neuronal MAPs as well as being the largest (350KD) . MAPs include MAP1A, MAP1B, and MAP2. MAP1a is a single-copy gene spanning 10.5 kb. MAP1a coding sequence is contained in five exons. MAP1B is encoded as a polyprotein that is processed to form a complex N-terminal microtubule-binding domain.

Synonyms

Microtubule-associated protein 1A; MAP-1A; MAP1A heavy chain; MAP1 light chain LC2; Map1a; Mtap1a

Gene Name

MAP1A

Gene ID

Human (4130), Mouse (17754), Rat (25152)

UniProt

P34926

Host

Mouse

Reactivity

Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

Rat brain microtubule-associated proteins (MAPs) .

Clonality

Monoclonal

Clone

Clone: HM-1

Tissue Specificity

Brain, heart and muscle.

Applications

IHC, WB

Field of Research

Cytoskeleton, Cytoskeleton/ECM, Microtubules, Neurogenesis, Neurology Process, Neuroscience, Signal Transduction

Purification

Ascites

Concentration

Adding 1 ml of PBS buffer will yield a concentration of 100 μg/ml.

Form

Lyophilized

Reconstitution

Add 1ml of PBS buffer will yield a concentration of 100ug/ml.

Function

Structural protein involved in the filamentous cross- bridging between microtubules and other skeletal elements.

References & Citations

1. Fink, J. K.; Jones, S. M.; Esposito, C.; Wilkowski, J. : Human microtubule-associated protein 1a (MAP1A) gene: genomic organization, cDNA sequence, and developmental-and tissue-specific expression. Genomics 35: 577-585, 1996. 2. Ammarback, J. A.; Obar, R. A.; Hughes, S. M.; Vallee, R. B. : MAP1B is encoded as a polyprotein that is processed to form a complex N-terminal microtubule-binding domain. Neuron 7: 129-139, 1991.

Storage Conditions

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

299531 MW

Observed Molecular Weight

42 kDa

Specificity

No cross reactivity with other proteins.

Gene Name Synonym

Microtubule-associated protein 1A

Subcellular Location

Cytoplasm, cytoskeleton .

Sequence Similarities

Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.

Protein Name

Microtubule-associated protein 1A

Isotype

Mouse IgG1

Contents

Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.