Anti-MAP2 Antibody (Monoclonal, HM-2)

About this product

Boster Bio Anti-MAP2 Antibody (Monoclonal, HM-2) catalog # MA1057. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number

MA1057

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

MAP2, a 280-kD protein, is highly concentrated in neuronal somata and dendrites. Microtubule-associated protein 2 (MAP2) is a neurosteroid receptor. MAP2 gene contains 19 exons, and located in segment 2q34-q35. The transgenic MAP2c was present in dendrites but not in axons but transgenic MAP2c messenger RNA was limited to cell bodies.

Synonyms

Microtubule-associated protein 2; MAP-2; Map2; Mtap2

Gene Name

MAP2

Gene ID

Human (4133), Mouse (17756), Rat (25595)

UniProt

P15146

Host

Mouse

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

Rat brain microtubule-associated proteins (MAPs) .

Clonality

Monoclonal

Clone

Clone: HM-2

Applications

IHC, WB

Field of Research

Cell Type Marker, Cytoskeleton, Cytoskeleton/ECM, Microtubules, Neural Stem Cells, Neuron Marker, Neuroscience, Signal Transduction, Stem Cells

Purification

Ascites

Concentration

Adding 1 ml of PBS buffer will yield a concentration of 100 μg/ml.

Form

Lyophilized

Reconstitution

Add 1ml of PBS buffer will yield a concentration of 100ug/ml.

Function

The exact function of MAP2 is unknown but MAPs may stabilize the microtubules against depolymerization. They also seem to have a stiffening effect on microtubules.

References & Citations

1. MAP2, a 280-kD protein, is highly concentrated in neuronal somata and dendrites. Microtubule-associated protein 2 (MAP2) is a neurosteroid receptor. MAP2 gene contains 19 exons, and located in segment 2q34-q35. The transgenic MAP2c was present in dendrites but not in axons but transgenic MAP2c messenger RNA was limited to cell bodies.

Storage Conditions

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

202411 MW

Observed Molecular Weight

280 kDa

Specificity

No cross reactivity with other proteins.

Gene Name Synonym

Microtubule-associated protein 2

Subcellular Location

Cytoplasm, cytoskeleton .

Sequence Similarities

Contains 3 Tau/MAP repeats.

Protein Name

Microtubule-associated protein 2

Isotype

Mouse IgG1

Contents

Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.