Anti-p19INK4d Cdkn2d Antibody (Monoclonal, DCS-100)

Catalog number MA1075

Price for MA1075

Size / count 100 µg/Vial

About this product

Boster Bio Anti-p19INK4d Cdkn2d Antibody (Monoclonal, DCS-100) catalog # MA1075. Tested in IHC, ICC, WB applications. This antibody reacts with Human.

Specifications

Catalog number: MA1075
Size / count: 100 µg/Vial
Dry ice: No
Hazardous: No
Discontinued: No
Background: Cyclins are important in regulating the cell cycle through their formation of enzymatic complexes with various cyclin-dependent kinases. P19 (INK4d) also kowns as cyclin-dependent kinase inhibitor 2D, is one of the novel members of the mouse INK4 gene family. Okuda et al. (1995) described the cloning of the human INK4d gene (CDKN2D) . The predicted 166-amino acid protein is 86% identical to the mouse protein and about 45% identical to other human INK4 family members.
Synonyms: Cyclin-dependent kinase 4 inhibitor D; p19-INK4d; Cdkn2d
Gene Name: CDKN2D
Gene ID: Human (1032), Mouse (12581), Rat (494444)
UniProt: Q60773
Host: Mouse
Reactivity: Human
Cross Reactivity: No cross-reactivity with other proteins
Immunogen: Recombinant human p19INK4d.
Clonality: Monoclonal
Clone: Clone: DCS-100
Tissue Specificity: Expressed in spleen, liver and lung. Not detected in kidney, colon, stomach or brain. .
Applications: IHC, ICC, WB
Field of Research: Cancer, Cell Biology, Cell Cycle, Cell Cycle Inhibitors, Epigenetics and Nuclear Signaling, Oncoproteins/Suppressors, Tumor Suppressors
Purification: Ascites
Concentration: Adding 1 ml of PBS buffer will yield a concentration of 100 μg/ml.
Form: Lyophilized
Reconstitution: Add 1ml of PBS buffer will yield a concentration of 100ug/ml.
Function: Interacts strongly with CDK4 and CDK6 and inhibits them. .
References & Citations: 1. Hirai, H.; Roussel, M. F.; Kato, J.-Y.; Ashmun, R. A.; Sherr, C. J. : Novel INK4 proteins, p19 and p18, are specific inhibitors of cyclin D-dependent kinases CDK4 and CDK6. Molec. Cell. Biol. 15: 2672-2681, 1995. 2. tsuzaki, Y.; Miyazawa, K.; Yokota, T.; Hitomi, T.; Yamagishi, H.; Sakai, T. : Molecular cloning and characterization of the human p19 (INK4d) gene promoter. FEBS Lett. 517: 272-276, 2002.
Storage Conditions: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight: 17809 MW
Observed Molecular Weight: 18 kDa
Specificity: No cross reactivity with other proteins.
Gene Name Synonym: Cyclin-dependent kinase 4 inhibitor D
Subcellular Location: Nucleus . Cytoplasm .
Sequence Similarities: Belongs to the CDKN2 cyclin-dependent kinase inhibitor family.
Protein Name: Cyclin-dependent kinase 4 inhibitor D
Isotype: Mouse IgG1
Contents: Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.

Frequently Asked Questions

What is the catalog number for Anti-p19INK4d Cdkn2d Antibody (Monoclonal, DCS-100)?

The catalog number for Anti-p19INK4d Cdkn2d Antibody (Monoclonal, DCS-100) is MA1075.

What sizes are available for Anti-p19INK4d Cdkn2d Antibody (Monoclonal, DCS-100)?

Anti-p19INK4d Cdkn2d Antibody (Monoclonal, DCS-100) is available in the following size(s): 100 µg/Vial.

Is Anti-p19INK4d Cdkn2d Antibody (Monoclonal, DCS-100) in stock?

Anti-p19INK4d Cdkn2d Antibody (Monoclonal, DCS-100) is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-p19INK4d Cdkn2d Antibody (Monoclonal, DCS-100)?

The safety data sheet for Anti-p19INK4d Cdkn2d Antibody (Monoclonal, DCS-100) is available here: https://www.bosterbio.com/msds?sku=MA1075.

What is Anti-p19INK4d Cdkn2d Antibody (Monoclonal, DCS-100) used for?

Boster Bio Anti-p19INK4d Cdkn2d Antibody (Monoclonal, DCS-100) catalog # MA1075. Tested in IHC, ICC, WB applications. This antibody reacts with Human.

What is the sensitivity of this ELISA kit?

Assay sensitivity, including the minimum detectable dose, is listed on the datasheet. Kits that are assembled on order typically ship within 2-4 weeks.

Do you ship this product with dry ice?

Some products, including certain cell lines and biologics, require dry ice for transportation, which carries an additional fee shown clearly in your quotation. Dry ice delivery isn’t always possible to every destination due to transit time or local restrictions, so we check feasibility in advance and you must store the goods at the correct temperature the moment they arrive.

Is this product species cross-reactive?

Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.