Anti-Fibroblast growth factor 22 FGF22 Antibody Picoband®

About this product

Boster Bio Anti-Fibroblast growth factor 22 FGF22 Antibody catalog # PA1455. Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

PA1455

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

FGF22, Fibroblast growth factor 22, is a protein which in humans is encoded by the FGF22 gene. The FGF22 sequence in a genomic clone is assigned to 19p13.3. The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. In situ hybridization demonstrated expression in the inner root sheath of the hair follicle. FGF22 is involved in hair development.

Synonyms

Fibroblast growth factor 22; FGF-22; FGF22; UNQ2500/PRO5800

Gene Name

FGF22

Gene ID

27006

UniProt

Q9HCT0

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

A synthetic peptide corresponding to a sequence in the middle region of human FGF22, different from the related mouse and rat sequences by one amino acid.

Clonality

Polyclonal

Applications

WB

Field of Research

Growth Factors/Hormones, Signal Transduction

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

Plays a role in the fasting response, glucose homeostasis, lipolysis and lipogenesis. Can stimulate cell proliferation (in vitro) . May be involved in hair development. .

References & Citations

1. Nakatake, Y., Hoshikawa, M., Asaki, T., Kassai, Y., Itoh, N.Identification of a novel fibroblast growth factor, FGF-22, preferentially expressed in the inner root sheath of the hair follicle.Biochim. Biophys. Acta 1517: 460-463, 2001. 2. Terauchi, A., Johnson-Venkatesh, E. M., Toth, A. B., Javed, D., Sutton, M. A., Umemori, H.Distinct FGFs promote differentiation of excitatory and inhibitory synapses.Nature 465: 783-787, 2010. 3. Umemori, H., Linhoff, M. W., Ornitz, D. M., Sanes, J. R. FGF22 and its close relatives are presynaptic organizing molecules in the mammalian brain.Cell 118: 257-270, 2004.

Storage Conditions

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

19663 MW

Observed Molecular Weight

24 kDa

Specificity

No cross reactivity with other proteins.

Gene Name Synonym

Fibroblast growth factor 22

Subcellular Location

Secreted .

Sequence Similarities

Belongs to the heparin-binding growth factors family.

Protein Name

Fibroblast growth factor 22 (FGF-22)

Isotype

Rabbit IgG

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.