Anti-Somatostatin/SST Antibody Picoband®

About this product

Boster Bio Anti-Somatostatin/SST Antibody catalog # PA2054. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

PA2054

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

SST (Somatostatin), also known as SMST, is a peptide hormone. Naylor et al. (1983) assigned the somatostatin gene to chromosome 3 by analyzing somatic cell hybrids with a polymorphic gene probe. Yacubova and Komuro (2002) examined the effects of somatostatin in cerebellar granule cells of early postnatal mice, because these cells express all 5 types of somatostatin receptors before the initiation of their migration. Saito et al. (2005) found that somatostatin modulated the proteolytic degradation of beta-amyloid catalyzed by neprilysin both in vitro and in vivo.

Synonyms

Somatostatin; Growth hormone release-inhibiting factor; Somatostatin-28; Somatostatin-14; SST

Gene Name

SST

Gene ID

6750

UniProt

P61278

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of human Somatostatin, identical to the related rat and mouse sequences.

Clonality

Polyclonal

Tissue Specificity

Widely expressed at a high level in skeletal muscle and at a weak level in thymus. Expressed in epithelial dysplasias and squamous cell carcinoma. .

Applications

IHC, WB

Field of Research

DNA/RNA, DNA Damage & Repair, DNA Damage Response, Epigenetics and Nuclear Signaling, Metabolic Signaling Pathways, Metabolism, Nucleotide Metabolism, Oncoproteins/Suppressors, p53 Pathway, Pathways and Processes, Tumor Suppressors

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

Somatostatin inhibits the release of somatotropin.

References & Citations

1. Naylor, S. L., Sakaguchi, A. Y., Shen, L.-P., Bell, G. I., Rutter, W. J., Shows, T. B. Polymorphic human somatostatin gene is located on chromosome 3. Proc. Nat. Acad. Sci. 80: 2686-2689, 1983. 2. Saito, T., Iwata, N., Tsubuki, S., Takaki, Y., Takano, J., Huang, S.-M., Suemoto, T., Higuchi, M., Saido, T. C. Somatostatin regulates brain amyloid beta-peptide A-beta-42 through modulation of proteolytic degradation. Nature Med. 11: 434-439, 2005. 3. Yacubova, E., Komuro, H. Stage-specific control of neuronal migration by somatostatin. Nature 415: 77-81, 2002.

Storage Conditions

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

12736 MW

Observed Molecular Weight

83 kDa

Specificity

No cross reactivity with other proteins.

Gene Name Synonym

Somatostatin

Subcellular Location

Secreted.

Sequence Similarities

Belongs to the somatostatin family.

Protein Name

Somatostatin

Isotype

Rabbit IgG

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.