Anti-Phospho-GluR1 (S845) GRIA1 Rabbit Monoclonal Antibody

About this product

Boster Bio Anti-Phospho-GluR1 (S845) GRIA1 Rabbit Monoclonal Antibody catalog # P02677. Tested in WB application. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number

P02677

Size / count

100 µL/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Phospho Site

S845

Synonyms

Glutamate receptor 1; GluR-1; AMPA-selective glutamate receptor 1; GluR-A; GluR-K1; Glutamate receptor ionotropic, AMPA 1; GluA1; Gria1; Glur1

Gene Name

GRIA1

Gene ID

2890

UniProt

P42261

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human GluR1

Clonality

Monoclonal

Clone

Clone: GFH-7

Tissue Specificity

Detected in cerebellum (at protein level) . .

Applications

WB

Field of Research

Ligand-Gated Ion Channels, Neuroscience, Neurotransmission, Receptors / Channels

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L- glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

101579 MW

Observed Molecular Weight

40 kDa

Gene Name Synonym

Glutamate receptor 1

Subcellular Location

Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane, postsynaptic density . Cell projection, dendrite . Cell projection, dendritic spine . Interaction with CACNG2, CNIH2 and CNIH3 promotes cell surface expression.

Protein Name

Glutamate receptor 1

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.