Anti-Phospho-c-Myc (S62) Rabbit Monoclonal Antibody

About this product

Boster Bio Anti-Phospho-c-Myc (S62) Rabbit Monoclonal Antibody catalog # P00026-2. Tested in WB, IHC, ICC/IF, IP applications. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number

P00026-2

Size / count

100 µL/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

Myc proto-oncogene protein; Class E basic helix-loop-helix protein 39; bHLHe39; Proto-oncogene c-Myc; Transcription factor p64; MYC; BHLHE39

Gene Name

MYC

Gene ID

4609

UniProt

P01106

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human Phospho-c-Myc (S62)

Clonality

Monoclonal

Clone

Clone: EAC-13

Tissue Specificity

Expressed in prostate cancer and levels increase from the normal to the malignant state (at protein level) . Expressed in all human cell types so far analyzed. The Tyr-176 phosphorylated form shows a significant increase in expression in breast cancers during the progressive stages i.e. normal to hyperplasia (ADH), ductal carcinoma in situ (DCIS), invasive ductal carcinoma (IDC) and lymph node metastatic (LNMM) stages. .

Applications

WB, IHC, ICC, IF, IP

Field of Research

Cancer, Cell Cycle, Cell Differentiation, Domain Families, Epigenetics and Nuclear Signaling, Hlh/Leucine Zipper, Nuclear, Oncoproteins, Oncoproteins/Suppressors, Signaling Pathways, Stem Cells, TGF Beta, Transcription, Transcription Factors, Tumor Biomarkers

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'- CAC[GA]TG-3'. Activates the transcription of growth-related genes.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

48804 MW

Observed Molecular Weight

65 kDa

Gene Name Synonym

Myc proto-oncogene protein

Subcellular Location

Nucleus, nucleoplasm . Nucleus, nucleolus .

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.