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Product details

Anti-Phospho-CrkII (Tyr221) Rabbit Monoclonal Antibody

Catalog number P02533

Price for P02533

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Size / count 100 µL/Vial

About this product

Boster Bio Anti-Phospho-CrkII (Tyr221) Rabbit Monoclonal Antibody catalog # P02533. Tested in WB, ICC/IF applications. This antibody reacts with Human.

Specifications

Catalog number
P02533
Size / count
100 µL/Vial
Dry ice
No
Hazardous
No
Discontinued
No
Phospho Site
Tyr221
Synonyms
Adapter molecule crk; Proto-oncogene c-Crk; p38; CRK
Gene Name
CRK
Gene ID
1398
UniProt
P46108
Host
Rabbit
Reactivity
Human
Immunogen
A synthesized peptide derived from human Phospho-CrkII (Tyr221)
Clonality
Monoclonal
Clone
Clone: FDE-3
Tissue Specificity
Expressed in brain, and to a lesser extent in lung, kidney and testis.
Applications
WB, ICC, IF
Field of Research
Adapters, Cancer, Cytoplasmic, Signal Transduction
Purification
Affinity-chromatography
Concentration
0.5mg/ml
Form
Liquid
Function
The Crk-I and Crk-II forms differ in their biological activities. Crk-II has less transforming activity than Crk-I. Crk- II mediates attachment-induced MAPK8 activation, membrane ruffling and cell motility in a Rac-dependent manner. Involved in phagocytosis of apoptotic cells and cell motility via its interaction with DOCK1 and DOCK4. May regulate the EFNA5-EPHA3 signaling. .
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
33831 MW
Observed Molecular Weight
85 kDa
Gene Name Synonym
Adapter molecule crk
Subcellular Location
Cytoplasm . Cell membrane . Translocated to the plasma membrane upon cell adhesion. .
Isotype
Rabbit IgG
Contents
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Frequently Asked Questions

What is the catalog number for Anti-Phospho-CrkII (Tyr221) Rabbit Monoclonal Antibody?

The catalog number for Anti-Phospho-CrkII (Tyr221) Rabbit Monoclonal Antibody is P02533.

What sizes are available for Anti-Phospho-CrkII (Tyr221) Rabbit Monoclonal Antibody?

Anti-Phospho-CrkII (Tyr221) Rabbit Monoclonal Antibody is available in the following size(s): 100 µL/Vial.

Is Anti-Phospho-CrkII (Tyr221) Rabbit Monoclonal Antibody in stock?

Anti-Phospho-CrkII (Tyr221) Rabbit Monoclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-Phospho-CrkII (Tyr221) Rabbit Monoclonal Antibody?

The safety data sheet for Anti-Phospho-CrkII (Tyr221) Rabbit Monoclonal Antibody is available here: https://www.bosterbio.com/msds?sku=P02533.

What is Anti-Phospho-CrkII (Tyr221) Rabbit Monoclonal Antibody used for?

Boster Bio Anti-Phospho-CrkII (Tyr221) Rabbit Monoclonal Antibody catalog # P02533. Tested in WB, ICC/IF applications. This antibody reacts with Human.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.

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