Anti-Phospho-Histone H2A (S129) HIST1H2AB Rabbit Monoclonal Antibody

About this product

Boster Bio Anti-Phospho-Histone H2A (S129) HIST1H2AB Rabbit Monoclonal Antibody catalog # P30931. Tested in WB application. This antibody reacts with Yeast.

Specifications

Catalog number

P30931

Size / count

100 µL/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Phospho Site

S129

Synonyms

Histone H2A.2; HTA2; H2A2; YBL003C; YBL0103

Gene Name

HIST1H2AB

Gene ID

852283

UniProt

P04912

Host

Rabbit

Reactivity

Yeast

Immunogen

A synthesized peptide derived from yeast Phospho-Histone H2A (S129)

Clonality

Monoclonal

Clone

Clone: DEE-8

Tissue Specificity

Four types of regulatory chains are found: I- alpha, I-beta, II-alpha, and II-beta. Their expression varies among tissues and is in some cases constitutive and in others inducible.

Applications

WB

Field of Research

Epigenetics and Nuclear Signaling, Histones

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Core component of nucleosome which plays a central role in DNA double strand break (DSB) repair. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

13989 MW

Observed Molecular Weight

140 kDa, 130 kDa, 110 kDa

Gene Name Synonym

Histone H2A.2

Subcellular Location

Nucleus. Chromosome.

Protein Name

Synapsin-1

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.