Anti-Id1 Rabbit Monoclonal Antibody

About this product

Boster Bio Anti-Id1 Rabbit Monoclonal Antibody catalog # M00945. Tested in WB, IHC, ICC/IF, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number

M00945

Size / count

100 µL/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

DNA-binding protein inhibitor ID-1; Class B basic helix-loop-helix protein 24; bHLHb24; Inhibitor of DNA binding 1; Inhibitor of differentiation 1; ID1; BHLHB24, ID

Gene Name

ID1

Gene ID

3397

UniProt

P41134

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human Id1

Clonality

Monoclonal

Clone

Clone: ACC-9

Tissue Specificity

Expressed in the excretory system, thyroid gland and Wilms tumors.

Applications

WB, IHC, ICC, IF, Flow Cytometry

Field of Research

Angiogenesis, Cancer, Cancer Susceptibility, Domain Families, Epigenetics and Nuclear Signaling, Hlh/Leucine Zipper, Invasion/Microenvironment, Proto-Oncogenes, Signal Transduction, Transcription

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Transcriptional regulator (lacking a basic DNA binding domain) which negatively regulates the basic helix-loop-helix (bHLH) transcription factors by forming heterodimers and inhibiting their DNA binding and transcriptional activity. Implicated in regulating a variety of cellular processes, including cellular growth, senescence, differentiation, apoptosis, angiogenesis, and neoplastic transformation. Inhibits skeletal muscle and cardiac myocyte differentiation. Regulates the circadian clock by repressing the transcriptional activator activity of the CLOCK-ARNTL/BMAL1 heterodimer (By similarity) . .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

16133 MW

Observed Molecular Weight

33 kDa

Gene Name Synonym

DNA-binding protein inhibitor ID-1

Subcellular Location

Cytoplasm . Nucleus.

Protein Name

Glycogen synthase kinase-3 beta (gsk3b)

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.