Anti-NGF/Beta Ngf Rabbit Monoclonal Antibody

About this product

Boster Bio Anti-NGF/Beta Ngf Rabbit Monoclonal Antibody catalog # M00341. Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number

M00341

Size / count

100 µL/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

Beta-nerve growth factor; Beta-NGF; NGF; NGFB

Gene Name

NGF

Gene ID

4803

UniProt

P01138

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human NGF

Clonality

Monoclonal

Clone

Clone: BDE-14

Tissue Specificity

Expressed in thymus, peripheral leukocytes as T-cells and spleen. Isoforms A are preferentially expressed in effector T-cells (thymus and peripheral leukocytes) whereas isoforms B and isoforms C are preferentially expressed in naive T- cells (spleen) . Isoforms B are expressed in naive T-cells after first antigen exposure and isoforms A are expressed in effector T- cells after second antigen exposure. Isoforms IA are widely expressed but not detected in liver nor pancreas, neural expression is strongest in corpus callosum. Isoforms IB are expressed mostly in muscle, cerebellum, placenta and thymus, neural expression in fetal and adult brain, strongest in corpus callosum. .

Applications

WB, IHC, ICC, IF

Field of Research

Growth and Development, Mesenchymal Stem Cells, Neural Stem Cells, Neurology Process, Neuroscience, Stem Cells, Surface Molecules

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades through those receptor tyrosine kinase to regulate neuronal proliferation, differentiation and survival. Inhibits metalloproteinase dependent proteolysis of platelet glycoprotein VI (PubMed:20164177) . .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

26959 MW

Observed Molecular Weight

35 kDa

Gene Name Synonym

Beta-nerve growth factor

Subcellular Location

Secreted.

Protein Name

P2X purinoceptor 1

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.