Anti-PBR TSPO Rabbit Monoclonal Antibody

About this product

Boster Bio Anti-PBR TSPO Rabbit Monoclonal Antibody catalog # M01153. Tested in WB, IHC, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human, Mouse.

Specifications

Catalog number

M01153

Size / count

100 µL/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

Translocator protein; Mitochondrial benzodiazepine receptor; PKBS; Peripheral-type benzodiazepine receptor; PBR; TSPO; BZRP, MBR

Gene Name

TSPO

Gene ID

706

UniProt

P30536

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

A synthesized peptide derived from human PBR

Clonality

Monoclonal

Clone

Clone: DAG-20

Tissue Specificity

Found in many tissue types. Expressed at the highest levels under normal conditions in tissues that synthesize steroids. .

Applications

WB, IHC, ICC, IF, IP, Flow Cytometry

Field of Research

Apoptosis, Calcium Channels, Calcium Signaling, Cancer, Cardiovascular, Cell Biology, Cell Death, Cholesterol Metabolism, Lipid and Lipoprotein Metabolism, Lipid Metabolism, Lipids/Lipoproteins, Metabolic Signaling Pathways, Metabolism, Metabolism Processes, Mitochondrial, Mitochondrial Markers, Mitochondrial Metabolism, Pathways and Processes, Signal Transduction, Signaling Pathway

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Can bind protoporphyrin IX and may play a role in the transport of porphyrins and heme (By similarity) . Promotes the transport of cholesterol across mitochondrial membranes and may play a role in lipid metabolism (PubMed:24814875), but its precise physiological role is controversial. It is apparently not required for steroid hormone biosynthesis. Was initially identified as peripheral-type benzodiazepine receptor; can also bind isoquinoline carboxamides (PubMed:1847678) . .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

18828 MW

Observed Molecular Weight

40 kDa

Gene Name Synonym

Translocator protein

Subcellular Location

Mitochondrion membrane ; Multi-pass membrane protein .

Protein Name

Glycogen synthase kinase-3 beta (gsk3b)

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.