Anti-p73 Rabbit Monoclonal Antibody

About this product

Boster Bio Anti-p73 Rabbit Monoclonal Antibody catalog # M00688. Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human.

Specifications

Catalog number

M00688

Size / count

100 µL/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

Tumor protein p73; p53-like transcription factor; p53-related protein; TP73; P73

Gene Name

TP73

Gene ID

7161

UniProt

O15350

Host

Rabbit

Reactivity

Human

Immunogen

A synthesized peptide derived from human p73

Clonality

Monoclonal

Clone

Clone: EHI-20

Tissue Specificity

Expressed in striatal neurons of patients with Huntington disease (at protein level) . Brain, kidney, placenta, colon, heart, liver, spleen, skeletal muscle, prostate, thymus and pancreas. Highly expressed in fetal tissue. .

Applications

WB, IHC, ICC, IF

Field of Research

Apoptosis, Cell Biology, Intracellular, p53 Pathway

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

70 kDa

Observed Molecular Weight

73 kDa

Gene Name Synonym

Tumor protein p73

Subcellular Location

Nucleus . Cytoplasm. Accumulates in the nucleus in response to DNA damage.

Protein Name

T-cell surface glycoprotein CD4

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.