Anti-MCM2 Rabbit Monoclonal Antibody

About this product

Boster Bio Anti-MCM2 Rabbit Monoclonal Antibody catalog # M00374. Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number

M00374

Size / count

100 µL/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

DNA replication licensing factor MCM2;3.6.4.12; Minichromosome maintenance protein 2 homolog; Nuclear protein BM28; MCM2; BM28, CCNL1, CDCL1, KIAA0030

Gene Name

MCM2

Gene ID

4171

UniProt

P49736

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human MCM2

Clonality

Monoclonal

Clone

Clone: BCA-13

Tissue Specificity

Highly expressed in substantia nigra. .

Applications

WB, IHC, ICC, IF

Field of Research

DNA/RNA, DNA Synthesis, Epigenetics and Nuclear Signaling

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for the entry in S phase and for cell division. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

101896 MW

Observed Molecular Weight

31-45 kDa

Gene Name Synonym

DNA replication licensing factor MCM2

Subcellular Location

Nucleus .

Protein Name

T-cell surface glycoprotein CD4

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.