Anti-MCSF Rabbit Monoclonal Antibody

About this product

Boster Bio Anti-MCSF Rabbit Monoclonal Antibody catalog # M00620. Tested in WB, IHC, ICC/IF, IP applications. This antibody reacts with Human.

Specifications

Catalog number

M00620

Size / count

100 µL/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

Macrophage colony-stimulating factor 1; CSF-1; M-CSF; MCSF; Lanimostim; Processed macrophage colony-stimulating factor 1; CSF1

Gene Name

CSF1

Gene ID

1435

UniProt

P09603

Host

Rabbit

Reactivity

Human

Immunogen

A synthesized peptide derived from human MCSF

Clonality

Monoclonal

Clone

Clone: CGI-3

Tissue Specificity

Highly expressed in surface mucosal cells of respiratory tract and stomach epithelia. Overexpressed in a number of carcinomas. Also expressed in Barrett's esophagus epithelium and in the proximal duodenum. .

Applications

WB, IHC, ICC, IF, IP

Field of Research

Atherosclerosis, Cardiovascular, Cytokines, Immunology, Innate Immunity, Macrophage/Inflammation, Vascular Inflammation

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female fertility. Promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration. Plays a role in lipoprotein clearance. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

60179 MW

Observed Molecular Weight

250 kDa

Gene Name Synonym

Macrophage colony-stimulating factor 1

Subcellular Location

Cell membrane ; Single-pass type I membrane protein .

Protein Name

T-cell surface glycoprotein CD4

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.