Anti-GRK2 ADRBK1 Rabbit Monoclonal Antibody

About this product

Boster Bio Anti-GRK2 ADRBK1 Rabbit Monoclonal Antibody catalog # M01473. Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number

M01473

Size / count

100 µL/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

Beta-adrenergic receptor kinase 1; Beta-ARK-1;2.7.11.15; G-protein coupled receptor kinase 2; ADRBK1; BARK, BARK1, GRK2

Gene Name

ADRBK1

Gene ID

2156

UniProt

P25098

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human GRK2

Clonality

Monoclonal

Clone

Clone: EGE-1

Tissue Specificity

Expressed in peripheral blood leukocytes. .

Applications

WB, IHC

Field of Research

G Protein Signaling, Neuroscience, Neurotransmission, Receptors / Channels, Signal Transduction, Signaling Pathway

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them. Key regulator of LPAR1 signaling. Competes with RALA for binding to LPAR1 thus affecting the signaling properties of the receptor. Desensitizes LPAR1 and LPAR2 in a phosphorylation-independent manner. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

79574 MW

Observed Molecular Weight

51 kDa

Gene Name Synonym

Beta-adrenergic receptor kinase 1

Subcellular Location

Cytoplasm . Cell membrane .

Protein Name

Glycogen synthase kinase-3 beta (gsk3b)

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.