Anti-SHP2 PTPN11 Rabbit Monoclonal Antibody

About this product

Boster Bio Anti-SHP2 PTPN11 Rabbit Monoclonal Antibody catalog # M00150. Tested in WB, IHC, ICC/IF, IP applications. This antibody reacts with Human.

Specifications

Catalog number

M00150

Size / count

100 µL/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

Tyrosine-protein phosphatase non-receptor type 11;3.1.3.48; Protein-tyrosine phosphatase 1D; PTP-1D; Protein-tyrosine phosphatase 2C; PTP-2C; SH-PTP2; SHP-2; Shp2; SH-PTP3; PTPN11; PTP2C, SHPTP2

Gene Name

PTPN11

Gene ID

5781

UniProt

Q06124

Host

Rabbit

Reactivity

Human

Immunogen

A synthesized peptide derived from human SHP2

Clonality

Monoclonal

Clone

Clone: GCA-16

Tissue Specificity

Widely expressed, with highest levels in heart, brain, and skeletal muscle. .

Applications

WB, IHC, ICC, IF, IP

Field of Research

Auditory System, Neuroscience, Protein Phosphorylation, Sensory System, Signal Transduction, Tyrosine Phosphatases

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus. Dephosphorylates ROCK2 at Tyr-722 resulting in stimulatation of its RhoA binding activity. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

68436 MW

Observed Molecular Weight

34 kDa

Gene Name Synonym

Tyrosine-protein phosphatase non-receptor type 11

Subcellular Location

Cytoplasm.

Protein Name

P2X purinoceptor 1

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.