Anti-Gli1 Rabbit Monoclonal Antibody

About this product

Boster Bio Anti-Gli1 Rabbit Monoclonal Antibody catalog # M00527. Tested in WB application. This antibody reacts with Human.

Specifications

Catalog number

M00527

Size / count

100 µL/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

Zinc finger protein GLI1; Glioma-associated oncogene; Oncogene GLI; GLI1; GLI

Gene Name

GLI1

Gene ID

2735

UniProt

P08151

Host

Rabbit

Reactivity

Human

Immunogen

A synthesized peptide derived from human Gli1

Clonality

Monoclonal

Clone

Clone: GCG-7

Tissue Specificity

Testis, myometrium and fallopian tube. Also expressed in the brain with highest expression in the cerebellum, optic nerve and olfactory tract. .

Applications

WB

Field of Research

Cancer, Domain Families, Epigenetics and Nuclear Signaling, Krueppel Like Factor, Neural Signal Transduction, Neurology Process, Neuroscience, Nuclear, Oncoproteins/Suppressors, Signaling Pathways, Stem Cells, Transcription, Tumor Suppressors, Zinc Finger

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Acts as a transcriptional activator. May regulate the transcription of specific genes during normal development. May play a role in craniofacial development and digital development, as well as development of the central nervous system and gastrointestinal tract. Mediates SHH signaling and thus cell proliferation and differentiation. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

117904 MW

Observed Molecular Weight

40 kDa

Applications Notes

WB 1:500-1:1000

Gene Name Synonym

Zinc finger protein GLI1

Subcellular Location

Cytoplasm. Nucleus. Tethered in the cytoplasm by binding to SUFU. Activation and translocation to the nucleus is promoted by interaction with STK36. Phosphorylation by ULK3 may promote nuclear localization. Translocation to the nucleus is promoted by interaction with ZIC1.

Protein Name

T-cell surface glycoprotein CD4

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.