Anti-IRS1 Rabbit Monoclonal Antibody

About this product

Boster Bio Anti-IRS1 Rabbit Monoclonal Antibody catalog # M00268. Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human.

Specifications

Catalog number

M00268

Size / count

100 µL/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

Insulin receptor substrate 1; IRS-1; IRS1

Gene Name

IRS1

Gene ID

3667

UniProt

P35568

Host

Rabbit

Reactivity

Human

Immunogen

A synthesized peptide derived from human IRS1

Clonality

Monoclonal

Clone

Clone: GIF-9

Tissue Specificity

Highly expressed in prostate and ESR1-positive breast tumors. Overexpressed in esophageal and lung adenocarcinomas. .

Applications

WB, IHC, ICC, IF

Field of Research

Adapters, Atherosclerosis, Cancer, Cardiovascular, Cell Type Markers, Cytoplasmic, Diabetes, Diabetes-associated, Growth Factors/Hormones, Heart Disease, Metabolism, Neurology Process, Neuroscience, Obesity, Signal Transduction, Tags & Cell Markers, Tumor Associated

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit (By similarity) . .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

131591 MW

Observed Molecular Weight

75 kDa

Gene Name Synonym

Insulin receptor substrate 1

Subcellular Location

Nucleus .

Protein Name

P2X purinoceptor 1

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.