Anti-IRF2 Rabbit Monoclonal Antibody

About this product

Boster Bio Anti-IRF2 Rabbit Monoclonal Antibody catalog # M02935. Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human, Mouse.

Specifications

Catalog number

M02935

Size / count

100 µL/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

Interferon regulatory factor 2; IRF-2; IRF2

Gene Name

IRF2

Gene ID

3660

UniProt

P14316

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

A synthesized peptide derived from human IRF2

Clonality

Monoclonal

Clone

Clone: HAC-9

Tissue Specificity

Expressed throughout the epithelium of the colon. Also expressed in lamina propria. .

Applications

WB, IHC, ICC, IF

Field of Research

Cytokines, Domain Families, Epigenetics and Nuclear Signaling, Hlh/Leucine Zipper, Immunology, Innate Immunity, Interferons, Pol II Transcription, Polymerase Associated Factors, Transcription, Transcription Factors

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS) ) and represses those genes. Also acts as an activator for several genes including H4 and IL7. Constitutively binds to the ISRE promoter to activate IL7. Involved in cell cycle regulation through binding the site II (HiNF-M) promoter region of H4 and activating transcription during cell growth. Antagonizes IRF1 transcriptional activation. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

39354 MW

Observed Molecular Weight

54 kDa

Gene Name Synonym

Interferon regulatory factor 2

Subcellular Location

Nucleus.

Protein Name

T-cell surface glycoprotein CD3 zeta chain

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.