Anti-MGMT Rabbit Monoclonal Antibody

About this product

Boster Bio Anti-MGMT Rabbit Monoclonal Antibody catalog # M01012. Tested in WB, IHC applications. This antibody reacts with Human.

Specifications

Catalog number

M01012

Size / count

100 µL/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

Methylated-DNA--protein-cysteine methyltransferase;2.1.1.63;6-O-methylguanine-DNA methyltransferase; MGMT; O-6-methylguanine-DNA-alkyltransferase; MGMT

Gene Name

MGMT

Gene ID

4255

UniProt

P16455

Host

Rabbit

Reactivity

Human

Immunogen

A synthesized peptide derived from human MGMT

Clonality

Monoclonal

Clone

Clone: IDD-13

Tissue Specificity

Plasma.

Applications

WB, IHC

Field of Research

DNA/RNA, DNA Damage & Repair, Epigenetics and Nuclear Signaling

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

21646 MW

Observed Molecular Weight

22 kDa

Gene Name Synonym

Methylated-DNA--protein-cysteine methyltransferase

Subcellular Location

Nucleus.

Protein Name

Glycogen synthase kinase-3 beta (gsk3b)

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.