Anti-Noxa Rabbit Monoclonal Antibody

About this product

Boster Bio Anti-Noxa Rabbit Monoclonal Antibody catalog # M02287. Tested in WB application. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number

M02287

Size / count

100 µL/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

Phorbol-12-myristate-13-acetate-induced protein 1; PMA-induced protein 1; Immediate-early-response protein APR; Protein Noxa; PMAIP1; NOXA

Gene Name

PMAIP1

Gene ID

5366

UniProt

Q13794

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human Noxa

Clonality

Monoclonal

Clone

Clone: AAFB-16

Tissue Specificity

Highly expressed in adult T-cell leukemia cell line.

Applications

WB

Field of Research

Angiogenesis, Cancer, Cytokines, Immunology, Innate Immunity, Invasion/Microenvironment

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Promotes activation of caspases and apoptosis. Promotes mitochondrial membrane changes and efflux of apoptogenic proteins from the mitochondria. Contributes to p53/TP53-dependent apoptosis after radiation exposure. Promotes proteasomal degradation of MCL1. Competes with BAK1 for binding to MCL1 and can displace BAK1 from its binding site on MCL1 (By similarity) . Competes with BIM/BCL2L11 for binding to MCL1 and can displace BIM/BCL2L11 from its binding site on MCL1. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

6030 MW

Observed Molecular Weight

16 kDa

Gene Name Synonym

Phorbol-12-myristate-13-acetate-induced protein 1

Subcellular Location

Mitochondrion .

Protein Name

Lysosome-associated membrane glycoprotein 2 (Lamp2)

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.