Anti-Bcl-2 Rabbit Monoclonal Antibody

About this product

Anti-Bcl-2

Specifications

Catalog number

M00040-1

Size / count

100 µL/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

Apoptosis regulator Bcl-2; BCL2

Gene Name

BCL2

Gene ID

596

UniProt

P10415

Host

Rabbit

Reactivity

Human

Immunogen

A synthesized peptide derived from human Bcl-2

Clonality

Monoclonal

Clone

Clone: HF-2

Tissue Specificity

Expressed in a variety of tissues.

Applications

WB, IHC, ICC, IF, IP, Flow Cytometry

Field of Research

Oncoproteins, Oncoproteins/Suppressors, Pathways and Processes, Response To Hypoxia, Signal Transduction, Tumor Biomarkers

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1) . .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

26266 MW

Observed Molecular Weight

83, 88 kDa

Gene Name Synonym

Apoptosis regulator Bcl-2

Subcellular Location

Mitochondrion outer membrane ; Single-pass membrane protein . Nucleus membrane ; Single-pass membrane protein . Endoplasmic reticulum membrane ; Single-pass membrane protein .

Protein Name

P2X purinoceptor 1

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.