Anti-APAF1 Rabbit Monoclonal Antibody

About this product

Boster Bio Anti-APAF1 Rabbit Monoclonal Antibody catalog # M00889. Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human, Mouse.

Specifications

Catalog number

M00889

Size / count

100 µL/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

Apoptotic protease-activating factor 1; APAF-1; APAF1; KIAA0413

Gene Name

APAF1

Gene ID

317

UniProt

O14727

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

A synthesized peptide derived from human APAF1

Clonality

Monoclonal

Clone

Clone: BHF-1

Tissue Specificity

Ubiquitous. Highest levels of expression in adult spleen and peripheral blood leukocytes, and in fetal brain, kidney and lung. Isoform 1 is expressed in heart, kidney and liver.

Applications

WB, IHC, ICC, IF

Field of Research

Apoptosis, Apoptotic Markers, Cancer, Cell Biology, Cell Death, Invasion/Microenvironment, Metabolism, Metabolism Processes, Mitochondrial, Mitochondrial Markers, Mitochondrial Metabolism, Pathways and Processes

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. Isoform 6 is less effective in inducing apoptosis. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

141840 MW

Observed Molecular Weight

52 kDa

Gene Name Synonym

Apoptotic protease-activating factor 1

Subcellular Location

Cytoplasm .

Protein Name

Glycogen synthase kinase-3 beta (gsk3b)

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.