Anti-SUZ12 Rabbit Monoclonal Antibody

About this product

Boster Bio Anti-SUZ12 Rabbit Monoclonal Antibody catalog # M00583. Tested in WB, ICC/IF, IP applications. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number

M00583

Size / count

100 µL/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

Polycomb protein SUZ12; Chromatin precipitated E2F target 9 protein; ChET 9 protein; Joined to JAZF1 protein; Suppressor of zeste 12 protein homolog; SUZ12; CHET9, JJAZ1, KIAA0160

Gene Name

SUZ12

Gene ID

23512

UniProt

Q15022

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human SUZ12

Clonality

Monoclonal

Clone

Clone: IEB-19

Tissue Specificity

Overexpressed in breast and colon cancer. .

Applications

WB, ICC, IF, IP

Field of Research

Chromatin Modifying Enzymes, Chromatin Remodeling, Developmental Families, Domain Families, Epigenetics and Nuclear Signaling, Methylation, Transcription

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Polycomb group (PcG) protein. Component of the PRC2/EED- EZH2 complex, which methylates 'Lys-9' (H3K9me) and 'Lys-27' (H3K27me) of histone H3, leading to transcriptional repression of the affected target gene. The PRC2/EED-EZH2 complex may also serve as a recruiting platform for DNA methyltransferases, thereby linking two epigenetic repression systems. Genes repressed by the PRC2/EED-EZH2 complex include HOXC8, HOXA9, MYT1 and CDKN2A. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

83055 MW

Observed Molecular Weight

47 kDa

Gene Name Synonym

Polycomb protein SUZ12

Subcellular Location

Nucleus .

Protein Name

T-cell surface glycoprotein CD4

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.