Anti-LAMP1/Cd107A Rabbit Monoclonal Antibody

About this product

Boster Bio Anti-LAMP1/Cd107A Rabbit Monoclonal Antibody catalog # M00780. Tested in WB, IHC applications. This antibody reacts with Human.

Specifications

Catalog number

M00780

Size / count

100 µL/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

Lysosome-associated membrane glycoprotein 1; LAMP-1; Lysosome-associated membrane protein 1; CD107 antigen-like family member A; CD107a; LAMP1

Gene Name

LAMP1

Gene ID

3916

UniProt

P11279

Host

Rabbit

Reactivity

Human

Immunogen

A synthesized peptide derived from human LAMP1

Clonality

Monoclonal

Clone

Clone: IIB-12

Tissue Specificity

Isoform 1 is widely expressed, other isoforms are generally coexpressed with a more restricted distribution. Isoform 2 is expressed in skin, liver, skeletal muscle, cardiac muscle, placenta, umbilical vein endothelial cells, neuroblastoma cells, lymphoma cells, hepatoma cells and astrocytoma cells. Isoform 3 and isoform 4 are expressed in muscle, kidney, liver, placenta, cervical epithelium, umbilical vein endothelial cells, fibroblast cells, embryonal kidney cells, platelets and several blood cell lines. Isoform 4, rather than isoform 3, is selectively expressed in peripheral T-cells. Isoform 3 is expressed in non- proliferating and differentiated prostate gland epithelial cells and in platelets, on the surface of erythroleukemia cells and in various hematopoietic cell lines. Isoform 5 is expressed specifically in striated muscle (skeletal and cardiac muscle) . .

Applications

WB, IHC

Field of Research

Cancer, Cell Death, Cell Type Marker, Hematopoietic Progenitors, Lymphoid, Metabolism, Metabolism Processes, Myeloid, Neurogenesis, Neurology Process, Neuron Marker, Neuroscience, Organelle Proteins, Organelles, Pathways and Processes, Protein Trafficking, Signal Transduction, Stem Cells, Subcellular Markers, T Lymphocytic Lineage, Tags & Cell Markers

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Presents carbohydrate ligands to selectins. Also implicated in tumor cell metastasis.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

44882 MW

Observed Molecular Weight

15 kDa

Gene Name Synonym

Lysosome-associated membrane glycoprotein 1

Subcellular Location

Cell membrane; Single-pass type I membrane protein. Endosome membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass type I membrane protein. Late endosome. This protein shuttles between lysosomes, endosomes, and the plasma membrane. Colocalizes with OSBPL1A at the late endosome.

Protein Name

T-cell surface glycoprotein CD4

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.