Anti-PRDX1/Peroxiredoxin 1 Rabbit Monoclonal Antibody

About this product

Boster Bio Anti-PRDX1/Peroxiredoxin 1 Rabbit Monoclonal Antibody catalog # M01845. Tested in WB, IHC, ICC/IF, Flow Cytometry applications. This antibody reacts with Human, Mouse.

Specifications

Catalog number

M01845

Size / count

100 µL/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

Peroxiredoxin-1;1.11.1.15; Natural killer cell-enhancing factor A; NKEF-A; Proliferation-associated gene protein; PAG; Thioredoxin peroxidase 2; Thioredoxin-dependent peroxide reductase 2; PRDX1; PAGA, PAGB, TDPX2

Gene Name

PRDX1

Gene ID

5052

UniProt

Q06830

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

A synthesized peptide derived from human PRDX1

Clonality

Monoclonal

Clone

Clone: IIG-16

Tissue Specificity

Weakly expressed in most tissues. Expressed at higher level in heart, brain, kidney and pancreas and also in liver, lung, placenta, prostate and kidney. .

Applications

WB, IHC, ICC, IF, Flow Cytometry

Field of Research

Atherosclerosis, Cardiovascular, Cell Biology, Metabolism, Oxidative Stress, Pathways and Processes, Redox Metabolism, Vascular Inflammation

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Involved in redox regulation of the cell. Reduces peroxides with reducing equivalents provided through the thioredoxin system but not from glutaredoxin. May play an important role in eliminating peroxides generated during metabolism. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H (2) O (2) . Reduces an intramolecular disulfide bond in GDPD5 that gates the ability to GDPD5 to drive postmitotic motor neuron differentiation (By similarity) . .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

22110 MW

Observed Molecular Weight

50 kDa

Gene Name Synonym

Peroxiredoxin-1

Subcellular Location

Cytoplasm . Melanosome . Identified by mass spectrometry in melanosome fractions from stage I to stage IV.

Protein Name

Lysosome-associated membrane glycoprotein 2 (Lamp2)

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.