Anti-GATA4 Rabbit Monoclonal Antibody

About this product

Boster Bio Anti-GATA4 Rabbit Monoclonal Antibody catalog # M00499-1. Tested in WB, ICC/IF, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number

M00499-1

Size / count

100 µL/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

Transcription factor GATA-4; GATA-binding factor 4; GATA4

Gene Name

GATA4

Gene ID

2626

UniProt

P43694

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human GATA4

Clonality

Monoclonal

Clone

Clone: ABOB-7

Tissue Specificity

Duodenum and pancreas (Langerhans islet beta cells and small subsets of endocrine non-beta-cells, at low levels in acinar cells) .

Applications

WB, ICC, IF, Flow Cytometry

Field of Research

Cancer, Cardiovascular, Developmental Biology, Domain Families, Epigenetics and Nuclear Signaling, Hypertrophy, Lineage Markers, Lineage Specification, Mesenchymal Stem Cells, Oncoproteins/Suppressors, Stem Cells, Transcription, Transcription Factors, Tumor Suppressors, Zinc Finger

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Transcriptional activator that binds to the consensus sequence 5'-AGATAG-3' and plays a key role in cardiac development (PubMed:24000169) . Involved in bone morphogenetic protein (BMP) - mediated induction of cardiac-specific gene expression (By similarity) . Binds to BMP response element (BMPRE) DNA sequences within cardiac activating regions (By similarity) . Acts as a transcriptional activator of ANF in cooperation with NKX2-5 (By similarity) . Promotes cardiac myocyte enlargement (PubMed:20081228) . Required during testicular development (PubMed:21220346) . May play a role in sphingolipid signaling by regulating the expression of sphingosine-1-phosphate degrading enzyme, spingosine-1-phosphate lyase (PubMed:15734735) . .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

44565 MW

Observed Molecular Weight

54 kDa

Gene Name Synonym

Transcription factor GATA-4

Subcellular Location

Nucleus .

Protein Name

T-cell surface glycoprotein CD4

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.