Anti-53BP1 TP53BP1 Rabbit Monoclonal Antibody — image 1 of 7

Product details

Anti-53BP1 TP53BP1 Rabbit Monoclonal Antibody

Catalog number M00397

Price for M00397

Size / count 100 µL/Vial

About this product

Boster Bio Anti-53BP1 TP53BP1 Rabbit Monoclonal Antibody catalog # M00397. Tested in WB, IHC, ICC/IF, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number: M00397
Size / count: 100 µL/Vial
Dry ice: No
Hazardous: No
Discontinued: No
Synonyms: Tumor suppressor p53-binding protein 1;53BP1; p53-binding protein 1; p53BP1; TP53BP1
Gene Name: TP53BP1
Gene ID: 7158
UniProt: Q12888
Host: Rabbit
Reactivity: Human, Mouse, Rat
Immunogen: A synthesized peptide derived from human 53BP1
Clonality: Monoclonal
Clone: Clone: ABAI-20
Tissue Specificity: Released primarily from activated T lymphocytes.
Applications: WB, IHC, ICC, IF, Flow Cytometry
Field of Research: Cancer, DNA/RNA, DNA Damage & Repair, DNA Damage Response, Epigenetics and Nuclear Signaling, Oncoproteins/Suppressors, p53 Pathway, Tumor Suppressors
Purification: Affinity-chromatography
Concentration: 0.5mg/ml
Form: Liquid
Function: Plays a key role in the response to DNA damage. May have a role in checkpoint signaling during mitosis. Enhances TP53- mediated transcriptional activation. .
Storage Conditions: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight: 213574 MW
Observed Molecular Weight: 450 kDa
Gene Name Synonym: Tumor suppressor p53-binding protein 1
Subcellular Location: Nucleus. Chromosome, centromere, kinetochore. Associated with kinetochores. Both nuclear and cytoplasmic in some cells. Recruited to sites of DNA damage, such as double stand breaks. H4K20me2 is required for efficient localization to double strand breaks and removal of proteins that have a high affinity for H4K20me2 such as L3MBTL1 and KDM4A is needed.
Protein Name: T-cell surface glycoprotein CD4
Isotype: Rabbit IgG
Contents: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Frequently Asked Questions

What is the catalog number for Anti-53BP1 TP53BP1 Rabbit Monoclonal Antibody?

The catalog number for Anti-53BP1 TP53BP1 Rabbit Monoclonal Antibody is M00397.

What sizes are available for Anti-53BP1 TP53BP1 Rabbit Monoclonal Antibody?

Anti-53BP1 TP53BP1 Rabbit Monoclonal Antibody is available in the following size(s): 100 µL/Vial.

Is Anti-53BP1 TP53BP1 Rabbit Monoclonal Antibody in stock?

Anti-53BP1 TP53BP1 Rabbit Monoclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-53BP1 TP53BP1 Rabbit Monoclonal Antibody?

The safety data sheet for Anti-53BP1 TP53BP1 Rabbit Monoclonal Antibody is available here: https://www.bosterbio.com/msds?sku=M00397.

What is Anti-53BP1 TP53BP1 Rabbit Monoclonal Antibody used for?

Boster Bio Anti-53BP1 TP53BP1 Rabbit Monoclonal Antibody catalog # M00397. Tested in WB, IHC, ICC/IF, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

What is the recommended storage temperature after reconstitution?

Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.