Anti-NR5A2/Lrh 1 Rabbit Monoclonal Antibody

About this product

Boster Bio Anti-NR5A2/Lrh 1 Rabbit Monoclonal Antibody catalog # M01332. Tested in WB application. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number

M01332

Size / count

100 µL/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

Nuclear receptor subfamily 5 group A member 2; Alpha-1-fetoprotein transcription factor; B1-binding factor; hB1F; CYP7A promoter-binding factor; Hepatocytic transcription factor; Liver receptor homolog 1; LRH-1; NR5A2; B1F, CPF, FTF

Gene Name

NR5A2

Gene ID

2494

UniProt

O00482

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human NR5A2

Clonality

Monoclonal

Clone

Clone: ABHO-14

Tissue Specificity

Abundantly expressed in pancreas, less in liver, very low levels in heart and lung. Expressed in the Hep-G2 cell line. Isoform 1 and isoform 2 seem to be present in fetal and adult liver and Hep-G2 cells.

Applications

WB

Field of Research

Developmental Biology, Embryogenesis, Embryonic Stem Cells, Epigenetics and Nuclear Signaling, Host-Virus Interaction, Interspecies Interaction, Intracellular, Microbiology, Stem Cells, Surface Molecules, Transcription

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Binds to the sequence element 5'-AACGACCGACCTTGAG-3' of the enhancer II of hepatitis B virus genes, a critical cis-element of their expression and regulation. May be responsible for the liver-specific activity of enhancer II, probably in combination with other hepatocyte transcription factors. Key regulator of cholesterol 7-alpha-hydroxylase gene (CYP7A) expression in liver. May also contribute to the regulation of pancreas-specific genes and play important roles in embryonic development.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

61331 MW

Observed Molecular Weight

105 kDa

Gene Name Synonym

Nuclear receptor subfamily 5 group A member 2

Subcellular Location

Nucleus .

Protein Name

Glycogen synthase kinase-3 beta (gsk3b)

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.