Anti-Atg4B Rabbit Monoclonal Antibody

About this product

Boster Bio Anti-Atg4B Rabbit Monoclonal Antibody catalog # M02885. Tested in WB, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number

M02885

Size / count

100 µL/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

Cysteine protease ATG4B;3.4.22.-; AUT-like 1 cysteine endopeptidase; Autophagin-1; Autophagy-related cysteine endopeptidase 1; Autophagy-related protein 4 homolog B; hAPG4B; ATG4B; APG4B, AUTL1, KIAA0943

Gene Name

ATG4B

Gene ID

23192

UniProt

Q9Y4P1

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human Atg4B

Clonality

Monoclonal

Clone

Clone: ABIA-1

Tissue Specificity

Mainly expressed in the skeletal muscle, followed by brain, heart, liver and pancreas. .

Applications

WB, Flow Cytometry

Field of Research

Cancer, Cardiovascular, Cell Biology, Cell Death, Extracellular Matrix, Invasion/Microenvironment, Metabolism, Metabolism Processes, Pathways and Processes, Proteolysis/Ubiquitin, Proteolytic Enzymes, Signal Transduction

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3, GABARAPL1, GABARAPL2 and GABARAP, to reveal a C-terminal glycine. Exposure of the glycine at the C- terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

44294 MW

Observed Molecular Weight

50 kDa

Gene Name Synonym

Cysteine protease ATG4B

Subcellular Location

Cytoplasm .

Protein Name

T-cell surface glycoprotein CD3 zeta chain

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.