Anti-TSG101 Rabbit Monoclonal Antibody

About this product

Boster Bio Anti-TSG101 Rabbit Monoclonal Antibody catalog # M01233. Tested in WB, IHC, ICC/IF, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number

M01233

Size / count

100 µL/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

Tumor susceptibility gene 101 protein; ESCRT-I complex subunit TSG101; TSG101

Gene Name

TSG101

Gene ID

7251

UniProt

Q99816

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human TSG101

Clonality

Monoclonal

Clone

Clone: IDG-20

Tissue Specificity

Heart, brain, placenta, lung, liver, skeletal, kidney and pancreas.

Applications

WB, IHC, ICC, IF, Flow Cytometry

Field of Research

Cancer, Cell Biology, Cell Cycle, Cell Cycle Inhibitors, Cell Differentiation, Epigenetics and Nuclear Signaling, Host-Virus Interaction, Interspecies Interaction, Microbiology

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs) . Mediates the association between the ESCRT-0 and ESCRT-I complex. Required for completion of cytokinesis; the function requires CEP55. May be involved in cell growth and differentiation. Acts as a negative growth regulator. Involved in the budding of many viruses through an interaction with viral proteins that contain a late-budding motif P-[ST]-A-P. This interaction is essential for viral particle budding of numerous retroviruses. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

43944 MW

Observed Molecular Weight

44 kDa

Gene Name Synonym

Tumor susceptibility gene 101 protein

Subcellular Location

Cytoplasm. Membrane; Peripheral membrane protein. Nucleus. Late endosome membrane; Peripheral membrane protein. Mainly cytoplasmic. Membrane-associated when active and soluble when inactive. Depending on the stage of the cell cycle, detected in the nucleus. Colocalized with CEP55 in the midbody during cytokinesis.

Protein Name

Glycogen synthase kinase-3 beta (gsk3b)

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.