Anti-MINA53 Rabbit Monoclonal Antibody

About this product

Boster Bio Anti-MINA53 Rabbit Monoclonal Antibody catalog # M00783. Tested in WB, ICC/IF applications. This antibody reacts with Human, Mouse.

Specifications

Catalog number

M00783

Size / count

100 µL/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

Bifunctional lysine-specific demethylase and histidyl-hydroxylase MINA;1.14.11.-;60S ribosomal protein L27a histidine hydroxylase; Histone lysine demethylase MINA; MYC-induced nuclear antigen; Mineral dust-induced gene protein; Nucleolar protein 52; Ribosomal oxygenase MINA; ROX; MINA ; MDIG , MINA53 , NO52

Gene Name

MINA

Gene ID

84864

UniProt

Q8IUF8

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

A synthesized peptide derived from human MINA53

Clonality

Monoclonal

Clone

Clone: AAAO-13

Tissue Specificity

Expressed in liver, skeletal muscle, heart, pancreas, and placenta. Not detected in brain, lung or kidney. Expressed in several lung cancer tissues, but is barely detected in the adjacent non-cancerous tissues. Also highly expressed in several esophageal squamous cell carcinoma (ESCC), and colon cancer tissues, and in various cancer cell lines. .

Applications

WB, ICC, IF

Field of Research

Chromatin Modifying Enzymes, Epigenetics and Nuclear Signaling

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. Is involved in the demethylation of trimethylated 'Lys-9' on histone H3 (H3K9me3), leading to an increase in ribosomal RNA expression. Also catalyzes the hydroxylation of 60S ribosomal protein L27a on 'His-39'. May play an important role in cell growth and survival. May be involved in ribosome biogenesis, most likely during the assembly process of pre-ribosomal particles. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

52800 MW

Observed Molecular Weight

15 kDa

Gene Name Synonym

Bifunctional lysine-specific demethylase and histidyl-hydroxylase MINA

Subcellular Location

Nucleus . Nucleus, nucleolus .

Protein Name

T-cell surface glycoprotein CD4

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.