Anti-FKBP12 Rabbit Monoclonal Antibody

About this product

Boster Bio Anti-FKBP12 Rabbit Monoclonal Antibody catalog # M04492. Tested in WB, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number

M04492

Size / count

100 µL/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

Peptidyl-prolyl cis-trans isomerase FKBP1A; PPIase FKBP1A;5.2.1.8;12 kDa FK506-binding protein;12 kDa FKBP; FKBP-12; Calstabin-1; FK506-binding protein 1A; FKBP-1A; Immunophilin FKBP12; Rotamase; FKBP1A; FKBP1, FKBP12

Gene Name

FKBP1A

Gene ID

2280

UniProt

P62942

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human FKBP12

Clonality

Monoclonal

Clone

Clone: AAFH-6

Tissue Specificity

Specifically expressed in stromal cells of breast carcinomas.

Applications

WB, ICC, IF

Field of Research

Immunology

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Keeps in an inactive conformation TGFBR1, the TGF-beta type I serine/threonine kinase receptor, preventing TGF-beta receptor activation in absence of ligand. Recruites SMAD7 to ACVR1B which prevents the association of SMAD2 and SMAD3 with the activin receptor complex, thereby blocking the activin signal. May modulate the RYR1 calcium channel activity. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

11951 MW

Observed Molecular Weight

12 kDa

Gene Name Synonym

Peptidyl-prolyl cis-trans isomerase FKBP1A

Subcellular Location

Cytoplasm.

Protein Name

T-cell surface glycoprotein CD3 zeta chain

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.