Anti-Sumo2/3 Rabbit Monoclonal Antibody

About this product

Boster Bio Anti-Sumo2/3 Rabbit Monoclonal Antibody catalog # M01282-2. Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number

M01282-2

Size / count

100 µL/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

Small ubiquitin-related modifier 2 ; SUMO-2 ; HSMT3 ; SMT3 homolog 2 ; SUMO-3 ; Sentrin-2 ; Ubiquitin-like protein SMT3B ; Smt3B ; SUMO2 ; SMT3B , SMT3H2

Gene Name

SUMO2

Gene ID

6613/6612

UniProt

P61956/P55854

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human Sumo2/3

Clonality

Monoclonal

Clone

Clone: IBG-19

Tissue Specificity

Broadly expressed. .

Applications

WB, IHC, ICC, IF

Field of Research

Adaptive Immunity, B Cells, Host-Virus Interaction, Human Protein, Immunology, Interspecies Interaction, Microbiology, Protein

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Ubiquitin-like protein that can be covalently attached to proteins as a monomer or as a lysine-linked polymer. Covalent attachment via an isopeptide bond to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by an E3 ligase such as PIAS1-4, RANBP2, CBX4 or ZNF451 (PubMed:26524494) . This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Polymeric SUMO2 chains are also susceptible to polyubiquitination which functions as a signal for proteasomal degradation of modified proteins (PubMed:18408734, PubMed:18538659, PubMed:21965678, PubMed:9556629) . Plays a role in the regulation of sumoylation status of SETX (PubMed:24105744) . .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

70 kDa

Gene Name Synonym

Small ubiquitin-related modifier 2

Subcellular Location

Nucleus. Nucleus, PML body.

Protein Name

Glycogen synthase kinase-3 beta (gsk3b)

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.