Anti-CD8 alpha Rabbit Monoclonal Antibody

About this product

Boster Bio Anti-CD8 alpha Rabbit Monoclonal Antibody catalog # M02236-2. Tested in IHC application. This antibody reacts with Human.

Specifications

Catalog number

M02236-2

Size / count

100 µL/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

T-cell surface glycoprotein CD8 alpha chain; T-lymphocyte differentiation antigen T8/Leu-2; CD8a; CD8A; MAL

Gene Name

CD8A

Gene ID

925

UniProt

P01732

Host

Rabbit

Reactivity

Human

Immunogen

A synthesized peptide derived from human CD8 alpha

Clonality

Monoclonal

Clone

Clone: BDG-3

Tissue Specificity

Expressed at high levels in adult kidney, skeletal and placenta tissues and at very low levels in adult heart, lung and brain tissues. .

Applications

IHC

Field of Research

Adaptive Immunity, Immunology, T Cells

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of T-cell mediated killing. CD8 alpha chains binds to class I MHC molecules alpha-3 domains.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

25729 MW

Observed Molecular Weight

75 kDa

Applications Notes

IHC 1:50-1:200

Gene Name Synonym

T-cell surface glycoprotein CD8 alpha chain

Subcellular Location

Isoform 1: Cell membrane; Single-pass type I membrane protein.

Protein Name

Lysosome-associated membrane glycoprotein 2 (Lamp2)

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.