Anti-Caspase-1 CASP1 Rabbit Monoclonal Antibody

About this product

Boster Bio Anti-Caspase-1 CASP1 Rabbit Monoclonal Antibody catalog # M00048. Tested in WB, IHC applications. This antibody reacts with Human, Rat.

Specifications

Catalog number

M00048

Size / count

100 µL/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

Caspase-1; CASP-1;3.4.22.36; Interleukin-1 beta convertase; IL-1BC; Interleukin-1 beta-converting enzyme; ICE; IL-1 beta-converting enzyme; p45; Caspase-1 subunit p20; Caspase-1 subunit p10; CASP1; IL1BC, IL1BCE

Gene Name

CASP1

Gene ID

834

UniProt

P29466

Host

Rabbit

Reactivity

Human, Rat

Immunogen

A synthesized peptide derived from human Caspase-1

Clonality

Monoclonal

Clone

Clone: DCB-3

Tissue Specificity

Expressed in larger amounts in spleen and lung. Detected in liver, heart, small intestine, colon, thymus, prostate, skeletal muscle, peripheral blood leukocytes, kidney and testis. No expression in the brain. .

Applications

WB, IHC

Field of Research

Apoptosis, Caspases, Cell Biology, Intracellular

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs) . Can also promote apoptosis. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

45159 MW

Observed Molecular Weight

35-48 kDa

Gene Name Synonym

Caspase-1

Subcellular Location

Cytoplasm.

Protein Name

P2X purinoceptor 1

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.