Anti-Profilin1 PFN1 Rabbit Monoclonal Antibody

About this product

Boster Bio Anti-Profilin1 PFN1 Rabbit Monoclonal Antibody catalog # M01480. Tested in WB, IHC, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number

M01480

Size / count

100 µL/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

Profilin-1; Epididymis tissue protein Li 184a; Profilin I; PFN1

Gene Name

PFN1

Gene ID

5216

UniProt

P07737

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human Profilin1

Clonality

Monoclonal

Clone

Clone: ABCD-16

Tissue Specificity

Expressed in epididymis (at protein level) . .

Applications

WB, IHC, ICC, IF, IP, Flow Cytometry

Field of Research

Tumor Suppressors

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. Inhibits androgen receptor (AR) and HTT aggregation and binding of G-actin is essential for its inhibition of AR. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

15054 MW

Observed Molecular Weight

59 kDa

Gene Name Synonym

Profilin-1

Subcellular Location

Cytoplasm, cytoskeleton.

Protein Name

Glycogen synthase kinase-3 beta (gsk3b)

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.