Anti-Human IgG IGHG1 Rabbit Monoclonal Antibody

About this product

Boster Bio Anti-Human IgG IGHG1 Rabbit Monoclonal Antibody catalog # M04575. Tested in WB, IHC applications. This antibody reacts with Human.

Specifications

Catalog number

M04575

Size / count

100 µL/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

Ig gamma-1 chain C region; IGHG1

Gene Name

IGHG1

UniProt

P01857/P01859/P01860/P01861

Host

Rabbit

Reactivity

Human

Immunogen

A synthesized peptide derived from human Human IgG

Clonality

Monoclonal

Clone

Clone: ABHF-9

Tissue Specificity

According to PubMed:9858585, highest levels of expression in adult testis, thymus and brain. Lower levels in placenta, spleen and colon. Consistently elevated levels in tumor- derived cells compared to non-transformed proliferating cells. According to PubMed:9840927: low levels in thymus, prostate, brain, skeletal muscle, and kidney. Elevated levels in lung. According to PubMed:9840943 highly expressed in testis, placenta, thymus and brain. In a lesser extent in small intestine and colon.

Applications

WB, IHC

Field of Research

Immunoglobulins, Immunology

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

36106 MW

Observed Molecular Weight

78 kDa

Gene Name Synonym

Ig gamma-1 chain C region

Subcellular Location

Secreted.

Protein Name

T-cell surface glycoprotein CD3 zeta chain

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.