Anti-Caveolin-2 CAV2 Rabbit Monoclonal Antibody

About this product

Boster Bio Anti-Caveolin-2 CAV2 Rabbit Monoclonal Antibody catalog # M01574. Tested in WB, IHC, ICC/IF, IP applications. This antibody reacts with Human.

Specifications

Catalog number

M01574

Size / count

100 µL/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

Caveolin-2; CAV2

Gene Name

CAV2

Gene ID

858

UniProt

P51636

Host

Rabbit

Reactivity

Human

Immunogen

A synthesized peptide derived from human Caveolin-2

Clonality

Monoclonal

Clone

Clone: FD-3

Tissue Specificity

Expressed in endothelial cells, smooth muscle cells, skeletal myoblasts and fibroblasts. .

Applications

WB, IHC, ICC, IF, IP

Field of Research

Calcium Channels, Calcium Signaling, Cancer, Cancer Metabolism, Energy Transfer Pathways, Integration Of Energy, Integration Of Energy Metabolism, Metabolic Signaling Pathway, Metabolic Signaling Pathways, Metabolism, Neuroscience, Neurotransmission, Pathways and Processes, Signal Transduction, Signaling Pathway

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

May act as a scaffolding protein within caveolar membranes. Interacts ly with G-protein alpha subunits and can functionally regulate their activity. Acts as an accessory protein in conjunction with CAV1 in targeting to lipid rafts and driving caveolae formation. The Ser-36 phosphorylated form has a role in modulating mitosis in endothelial cells. Positive regulator of cellular mitogenesis of the MAPK signaling pathway. Required for the insulin-stimulated nuclear translocation and activation of MAPK1 and STAT3, and the subsequent regulation of cell cycle progression (By similarity) . .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

18291 MW

Observed Molecular Weight

75 kDa

Gene Name Synonym

Caveolin-2

Subcellular Location

Nucleus. Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein. Cell membrane; Peripheral membrane protein. Membrane, caveola; Peripheral membrane protein. Potential hairpin-like structure in the membrane. Membrane protein of caveolae. Tyr-19-phosphorylated form is enriched at sites of cell-cell contact and is translocated to the nucleus in complex with MAPK1 in response to insulin (By similarity) . Tyr-27- phosphorylated form is located both in the cytoplasm and plasma membrane. CAV1-mediated Ser-23-phosphorylated form locates to the plasma membrane. Ser-36-phosphorylated form resides in intracellular compartments. .

Protein Name

Lysosome-associated membrane glycoprotein 2 (Lamp2)

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.