Anti-Stathmin 1 STMN1 Rabbit Monoclonal Antibody

About this product

Boster Bio Anti-Stathmin 1 STMN1 Rabbit Monoclonal Antibody catalog # M01194. Tested in WB, IHC, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number

M01194

Size / count

100 µL/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

Stathmin; Leukemia-associated phosphoprotein p18; Metablastin; Oncoprotein 18; Op18; Phosphoprotein p19; pp19; Prosolin; Protein Pr22; pp17; STMN1; C1orf215, LAP18, OP18

Gene Name

STMN1

Gene ID

3925

UniProt

P16949

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human Stathmin 1

Clonality

Monoclonal

Clone

Clone: DDA-19

Tissue Specificity

Ubiquitous. Expression is strongest in fetal and adult brain, spinal cord, and cerebellum, followed by thymus, bone marrow, testis, and fetal liver. Expression is intermediate in colon, ovary, placenta, uterus, and trachea, and is readily detected at substantially lower levels in all other tissues examined. Lowest expression is found in adult liver. Present in much greater abundance in cells from patients with acute leukemia of different subtypes than in normal peripheral blood lymphocytes, non-leukemic proliferating lymphoid cells, bone marrow cells, or cells from patients with chronic lymphoid or myeloid leukemia. .

Applications

WB, IHC, ICC, IF, IP, Flow Cytometry

Field of Research

Alzheimer's Disease, Cell Adhesion Proteins, Cytoskeleton, Cytoskeleton/ECM, Microtubules, Neurodegenerative Disease, Neurology Process, Neuroscience, Signal Transduction, Tubulin

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Involved in the regulation of the microtubule (MT) filament system by destabilizing microtubules. Prevents assembly and promotes disassembly of microtubules. Phosphorylation at Ser- 16 may be required for axon formation during neurogenesis. Involved in the control of the learned and innate fear (By similarity) . .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

17303 MW

Observed Molecular Weight

17 kDa

Gene Name Synonym

Stathmin

Subcellular Location

Cytoplasm, cytoskeleton.

Protein Name

Glycogen synthase kinase-3 beta (gsk3b)

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.