Anti-HIF-1 beta ARNT Rabbit Monoclonal Antibody

About this product

Boster Bio Anti-HIF-1 beta ARNT Rabbit Monoclonal Antibody catalog # M02263. Tested in WB, IHC applications. This antibody reacts with Human.

Specifications

Catalog number

M02263

Size / count

100 µL/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

Aryl hydrocarbon receptor nuclear translocator; ARNT protein; Class E basic helix-loop-helix protein 2; bHLHe2; Dioxin receptor, nuclear translocator; Hypoxia-inducible factor 1-beta; HIF-1-beta; HIF1-beta; ARNT; BHLHE2

Gene Name

ARNT

Gene ID

405

UniProt

P27540

Host

Rabbit

Reactivity

Human

Immunogen

A synthesized peptide derived from human HIF-1 beta

Clonality

Monoclonal

Clone

Clone: EAD-1

Tissue Specificity

Expressed in the brain, in oligodendrocytes. Strongly expressed in oligodendrogliomas, while expression is weak to moderate in astrocytomas. Expression in glioblastomas highly variable. .

Applications

WB, IHC

Field of Research

Cancer, Cancer Metabolism, Epigenetics and Nuclear Signaling, Metabolism, Metabolism Processes, Neural Signal Transduction, Neurology Process, Neuroscience, Pathways and Processes, Pol II Transcription, Polymerase Associated Factors, Response To Hypoxia, Transcription, Transcription Factors

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Required for activity of the Ah (dioxin) receptor. This protein is required for the ligand-binding subunit to translocate from the cytosol to the nucleus after ligand binding. The complex then initiates transcription of genes involved in the activation of PAH procarcinogens. The heterodimer with HIF1A or EPAS1/HIF2A functions as a transcriptional regulator of the adaptive response to hypoxia.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

86636 MW

Observed Molecular Weight

16 kDa

Gene Name Synonym

Aryl hydrocarbon receptor nuclear translocator

Subcellular Location

Nucleus.

Protein Name

Lysosome-associated membrane glycoprotein 2 (Lamp2)

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.