Anti-hnRNP C1/C2 Rabbit Monoclonal Antibody

Catalog number M02726

Price for M02726

Size / count 100 µL/Vial

About this product

Boster Bio Anti-hnRNP C1/C2 Rabbit Monoclonal Antibody catalog # M02726. Tested in WB, IHC, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number: M02726
Size / count: 100 µL/Vial
Dry ice: No
Hazardous: No
Discontinued: No
Synonyms: Heterogeneous nuclear ribonucleoproteins C1/C2; hnRNP C1/C2; HNRNPC; HNRPC
Gene Name: HNRNPC
Gene ID: 3183
UniProt: P07910
Host: Rabbit
Reactivity: Human, Mouse, Rat
Immunogen: A synthesized peptide derived from human hnRNP C1/C2
Clonality: Monoclonal
Clone: Clone: FEB-8
Tissue Specificity: Widely expressed.
Applications: WB, IHC, ICC, IF, IP, Flow Cytometry
Field of Research: Chromosome Structure, Epigenetics and Nuclear Signaling
Purification: Affinity-chromatography
Concentration: 0.5mg/ml
Form: Liquid
Function: Binds pre-mRNA and nucleates the assembly of 40S hnRNP particles (PubMed:8264621) . Specifically recognizes and binds N6- methyladenosine (m6A) -containing RNAs, a modification present at internal sites of mRNAs that affects mRNA splicing, processing and stability. M6A alters the local structure in mRNAs and long non- coding RNAs (lncRNAs) via a mechanism named 'm (6) A-switch' to facilitate binding of HNRNPC, leading to regulation of mRNA splicing (PubMed:25719671) . Single HNRNPC tetramers bind 230-240 nucleotides. Trimers of HNRNPC tetramers bind 700 nucleotides. May play a role in the early steps of spliceosome assembly and pre- mRNA splicing. Interacts with poly-U tracts in the 3'-UTR or 5'- UTR of mRNA and modulates the stability and the level of translation of bound mRNA molecules (PubMed:12509468, PubMed:16010978, PubMed:7567451, PubMed:8264621) . .
Storage Conditions: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight: 33670 MW
Observed Molecular Weight: 35-40 kDa
Gene Name Synonym: Heterogeneous nuclear ribonucleoproteins C1/C2
Subcellular Location: Nucleus. Component of ribonucleosomes.
Protein Name: T-cell surface glycoprotein CD3 zeta chain
Isotype: Rabbit IgG
Contents: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Frequently Asked Questions

What is the catalog number for Anti-hnRNP C1/C2 Rabbit Monoclonal Antibody?

The catalog number for Anti-hnRNP C1/C2 Rabbit Monoclonal Antibody is M02726.

What sizes are available for Anti-hnRNP C1/C2 Rabbit Monoclonal Antibody?

Anti-hnRNP C1/C2 Rabbit Monoclonal Antibody is available in the following size(s): 100 µL/Vial.

Is Anti-hnRNP C1/C2 Rabbit Monoclonal Antibody in stock?

Anti-hnRNP C1/C2 Rabbit Monoclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-hnRNP C1/C2 Rabbit Monoclonal Antibody?

The safety data sheet for Anti-hnRNP C1/C2 Rabbit Monoclonal Antibody is available here: https://www.bosterbio.com/msds?sku=M02726.

What is Anti-hnRNP C1/C2 Rabbit Monoclonal Antibody used for?

Boster Bio Anti-hnRNP C1/C2 Rabbit Monoclonal Antibody catalog # M02726. Tested in WB, IHC, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

What is the purity of this recombinant protein?

Purity, typically assessed by SDS-PAGE, is listed on the datasheet under quality control data.

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.