Anti-LDL Receptor Rabbit Monoclonal Antibody

About this product

Boster Bio Anti-LDL Receptor Rabbit Monoclonal Antibody catalog # M00076. Tested in WB, IHC applications. This antibody reacts with Human, Mouse.

Specifications

Catalog number

M00076

Size / count

100 µL/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

Low-density lipoprotein receptor; LDL receptor; LDLR

Gene Name

LDLR

Gene ID

3949

UniProt

P01130

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

A synthesized peptide derived from human LDL Receptor

Clonality

Monoclonal

Clone

Clone: BFC-12

Tissue Specificity

Brain and testis.

Applications

WB, IHC

Field of Research

Lipid Metabolism, Lipids/Lipoproteins, Metabolism, Signal Transduction

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

95376 MW

Observed Molecular Weight

70 kDa

Gene Name Synonym

Low-density lipoprotein receptor

Subcellular Location

Cell membrane; Single-pass type I membrane protein. Endomembrane system; Single-pass type I membrane protein. Membrane, clathrin-coated pit; Single-pass type I membrane protein. Golgi apparatus. Early endosome. Late endosome. Cell surface. Lysosome. Found distributed from the plasma membrane to intracellular compartments. Localizes to the Golgi apparatus, early and late endosomes/lysosomes and cell surface in the presence of PCSK9.

Protein Name

P2X purinoceptor 1

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.